National college has begun M.Sc. Biotechnology program since 2012 under the affiliation of Tribhuwan University with an aim to produce globally competent manpower. Biotechnology is one of the fastest growing and promising study sectors in the world. It develops a new product or process upon application of engineering technologies bon living organisms. It also known as a combination of biology and other engineering technologies. It covers wide variety of subjects like genetics, biochemistry, microbiology, immunology, virology, chemistry and engineering. As a field of applied biology, biotechnology has applications in various sectors such as health care, drug discovery, vaccine production, crops production, bio fuels, biodegradable plastics, vegetable oil, washing power, organic products, (including beer and milk products) biosensor, degradation of widely- diffused toxic compounds and nanotechnology etc.

Though there is a diverse opportunity to work in the field of biotechnology. Nepal is lagging to make it prime sector of employment opportunity and economic upliftment. Thus this program has targeted to fulfill such demands though research-oriented multidisciplinary subject.